Elevated Plasma Vitamin B12 Levels as a Marker for Cancer: A Population-Based Cohort Study

AbstractBackgroundA substantial proportion of patients referred for plasma vitamin B12 (cobalamin [Cbl]) measurement present with high Cbl levels, which have been reported in patients with different cancer types. However, the cancer risk among patients with newly diagnosed high Cbl levels has not b...

One-year risk of cancer in groups according to plasma cobalamin (Cbl) levels in 100 to 200 pmol/L intervals. The figure shows the 1-year standardized incidence ratios (SIRs) with corresponding 95% confidence intervals (CIs; vertical bars) disaggregated according to Cbl levels for hematological canc...

Risk of specific cancer types within the first year after plasma cobalamin (Cbl) measurement. The figure shows the 1-year standardized incidence ratios (SIRs) with corresponding 95% confidence intervals (CIs) disaggregated according to Cbl levels: x: 200 to 600 pmol/L; o: 601 to 800 pmol/L; and □...

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