doi: 10.1016/j.semarthrit.2019.06.008. Epub 2019 Jun 13.
Marie Voirin-Hertz 1 , Guillermo Carvajal Alegria 1 , Florent Garrigues 2 , Alexandre Simon 3 , Antoine Feydy 4 , Monique Reijnierse 5 , Désirée van der Heijde 6 , Damien Loeuille 7 , Pascal Claudepierre 8 , Thierry Marhadour 1 , Alain Saraux 9
Affiliations
- PMID: 31277929
- DOI: 10.1016/j.semarthrit.2019.06.008
Associations of lumbar scoliosis with presentation of suspected early axial spondyloarthritis
Marie Voirin-Hertz et al. Semin Arthritis Rheum. 2020 Feb.
Abstract
Objective: Scoliosis may impact the mechanical loading and cause secondary changes of the sacroiliac joints and lumbar spine. Our goal was to look how lumbar scoliosis modify the clinical and imaging-study in patients with recent-onset inflammatory back pain (IBP) suggesting axial spondyloarthritis (axSpA).
Methods: Baseline weight-bearing lumbar-spine radiographs obtained in the DESIR cohort of patients aged 18-50 years and having IBP for at least 3 months but less than 3 years suggesting axSpA were studied. After training on scoliosis detection based on Cobb's angle>10° plus Nash-Moe grade≥1, readers blinded to patient data measured spine lumbar scoliosis, sacral horizontal angle, lumbosacral angle and lumbar lordosis on the radiograph of the lumbar and scored sacroiliitis on the radiograph of the pelvis. Baseline MRIs T1 and STIR of the lumbar spine and sacroiliac joints were evaluated for respectively degenerative changes and signs of axSpA.
Results: Of the 360 patients (50.8% females) 88.7% had lumbar pain and 69.3% met ASAS criteria for axSpA. Mean Cobb's angle was 3.2°±5.0° and 28 (7.7%) patients had lumbar scoliosis. No statistical differences were observed for radiographic sacroiliitis, MRI sacroiliitis, modified Stoke Ankylosing Spondylitis Spinal Score, Pfirmmann score, high-intensity zone, protrusion, extrusion, MODIC score between patients with and without scoliosis. In both groups, degenerative changes by MRI were rare and predominated at L4-L5 and L5-S1.
Conclusion: In patients with early IBP suggesting axSpA, lumbar scoliosis was not associated with inflammatory or degenerative changes.
Keywords: Ankylosing spondylitis; Axial spondyloarthritis; Degenerative disease; Lumbar lordosis; Lumbar scoliosis; Sacral slope.
Copyright © 2019 Elsevier Inc. All rights reserved.
PubMed Disclaimer
Similar articles
-
Spinal-pelvic orientation: potential effect on the diagnosis of spondyloarthritis.
Carvajal Alegria G, Deloire L, Herbette M, Garrigues F, Gossec L, Simon A, Feydy A, Reijnierse M, van der Heijde D, Loeuille D, Claudepierre P, Marhadour T, Saraux A. Carvajal Alegria G, et al. Rheumatology (Oxford). 2020 Jan 1;59(1):84-89. doi: 10.1093/rheumatology/kez240. Rheumatology (Oxford). 2020. PMID: 31236597
-
Carvajal Alegria G, Voirin-Hertz M, Garrigues F, Herbette M, Deloire L, Simon A, Feydy A, Reijnierse M, van der Heijde D, Marhadour T, Saraux A. Carvajal Alegria G, et al. Rheumatology (Oxford). 2020 Jul 1;59(7):1679-1683. doi: 10.1093/rheumatology/kez520. Rheumatology (Oxford). 2020. PMID: 31670801
-
Sacroiliac and spine imaging in spondyloarthritis: Does phenotype or sex matter?
Pereira GC, Machado NP, Gomes AF, Assad RL, Carneiro FH, Azevedo VF. Pereira GC, et al. Adv Rheumatol. 2024 Sep 10;64(1):68. doi: 10.1186/s42358-024-00411-w. Adv Rheumatol. 2024. PMID: 39256831
-
[Magnetic resonance imaging (MRI) diagnostics in axial spondyloarthritis].
Witte T, Baraliakos X. Witte T, et al. Z Rheumatol. 2017 Sep;76(7):574-579. doi: 10.1007/s00393-017-0361-x. Z Rheumatol. 2017. PMID: 28812174 Review. German.
-
MRI of the sacroiliac joints: what is and what is not sacroiliitis?
Østergaard M. Østergaard M. Curr Opin Rheumatol. 2020 Jul;32(4):357-364. doi: 10.1097/BOR.0000000000000718. Curr Opin Rheumatol. 2020. PMID: 32453038 Review.
Cited by
-
Zhang Z, Zeng J, Li Y, Liao Q, Huang D, Zou Y, Liu G. Zhang Z, et al. Exp Ther Med. 2021 Sep;22(3):965. doi: 10.3892/etm.2021.10397. Epub 2021 Jul 7. Exp Ther Med. 2021. PMID: 34335907 Free PMC article.
-
Assessment of the association between paraspinal muscle degeneration and quality of life in patients with degenerative lumbar scoliosis.
Tang Y, Yang S, Chen C, Luo K, Chen Y, Wang D, Tan J, Dai Q, Zhang C, Wu W, Xu J, Luo F. Tang Y, et al. Exp Ther Med. 2020 Jul;20(1):505-511. doi: 10.3892/etm.2020.8682. Epub 2020 Apr 23. Exp Ther Med. 2020. PMID: 32509021 Free PMC article.