Ordering Recommendation

Recommendations when to order or not order the test. May include related or preferred tests.

Qualitative test to detect antibodies to John Cunningham (JC) virus. Aids in risk stratification for the development of progressive multifocal leukoencephalopathy (PML) in individuals with multiple sclerosis or Crohn’s disease who are receiving natalizumab therapy.

New York DOH Approval Status

Indicates whether a test has been approved by the New York State Department of Health.

This test is New York state approved.

Specimen Required

Patient PreparationInstructions patient must follow before/during specimen collection.

CollectSpecimen type to collect. May include collection media, tubes, kits, etc.

Plain red or serum separator tube (SST). Also acceptable: Lavender (K2EDTA)

Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.

Transfer 1 mL serum or plasma to an ARUP standard transport tube. (Min: 0.5 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.

Refrigerated. Also acceptable: Room temperature or frozen.

Unacceptable ConditionsCommon conditions under which a specimen will be rejected.

StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.

Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 months

Methodology

Process(es) used to perform the test.

Enzyme-Linked Immunosorbent Assay (ELISA)

Performed

Days of the week the test is performed.

Varies

Reported

Expected turnaround time for a result, beginning when ARUP has received the specimen.

6-10 days

Reference Interval

Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.

By report

Interpretive Data

May include disease information, patient result explanation, recommendations, or details of testing.

Compliance Category

Performed by non-ARUP Laboratory

Note

Additional information related to the test.

If antibody result is indeterminate, then a confirmation (inhibition) assay will be added.

CPT Codes

The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually.
CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ.
CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.

86711; if reflexed, add 86711

Components

Components of test

Component Test Code* Component Chart Name LOINC
3006255 JC Virus Index 100977-8
3006256 JC Virus Antibody 70173-0

* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Other names that describe the test. Synonyms.

  • JC polyoma virus
  • John Cunningham virus
  • natalizumab
  • progressive multifocal leukoencephalopathy (PML)
  • Stratify JCV Antibody with Index

JC Virus Antibody by ELISA, Serum with Reflex to Inhibition Assay

Quest Diagnostics San Juan Capistrano Inc.