Excessive eating and weight gain:A rare post-acute COVID-19 syndrome - PubMed

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The coronavirus disease - 2019 (COVID-19) is a multisystem illness associated with several metabolic derangements. Studies report that post-acute COVID-19 syndromes (PACs) continue to evolve, however, polyphagia is not uncommon. Herein, we report a rare occurrence of polyphagia in a patient followin …

Case Reports

Excessive eating and weight gain:A rare post-acute COVID-19 syndrome

Mark Mohan Kaggwa et al. Diabetes Metab Syndr. 2021 Sep-Oct.

Abstract

The coronavirus disease - 2019 (COVID-19) is a multisystem illness associated with several metabolic derangements. Studies report that post-acute COVID-19 syndromes (PACs) continue to evolve, however, polyphagia is not uncommon. Herein, we report a rare occurrence of polyphagia in a patient following acute COVID-19 illness. A-41-year-old Ugandan female with a negative past medical history presented with complains of excessive appetite, eating large amounts of food, inability to feel satisfied, failure to control desire to eat, and weight gain 6 months following recovery from a mild episode of acute COVID-19 pneumonia. Her body mass index rose to 30 Kg/m2 from 22 Kg/m2 prior to suffering from COVID-19. There was no history of polyuria, polydipsia, pruritus, or prior eating disorder or related history. Investigation found that brain computed tomography scan was normal, fasting blood sugar to be 5.6 mmol/L (normal range, 3.9-7.0 mmol/L), adrenocorticotropin hormone level to be 8.763 pg/mL (normal range, 6-40 pg/mL), erythrocyte sedimentation rate to be 12 mm/hour (0-30 mm/hour), but there was an elevation in glycosylated hemoglobin level (HbA1c, 7.7%). She was commenced on psychotherapy and behavioral changes with good outcomes. Polyphagia may be one of the rare PACs, requiring further research.

Keywords: COVID-19; Polyphagia; Post acute COVID-19 syndrome; Weight gain.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no conflict of interest.

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References

    1. Laflamme D. Canine and feline gastroenterology. Elsevier; 2013. Polyphagia and hyperphagia; pp. 148–150.
    1. Smith P.M., Ferguson A.V. Neurophysiology of hunger and satiety. Dev Disabil Res Rev. 2008;14(2):96–104. - PubMed
    1. Wynne K., et al. Appetite control. J Endocrinol. 2005;184(2):291–318. - PubMed
    1. Zheng K.I., et al. Extrapulmonary complications of COVID-19: a multisystem disease? J Med Virol. 2021;93(1):323–335. - PMC - PubMed
    1. Baig A.M. Deleterious outcomes in long-hauler COVID-19: the effects of SARS-CoV-2 on the CNS in chronic COVID syndrome. ACS Chem Neurosci. 2020;11(24):4017–4020. - PubMed

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